E-Books →Lentiviral Vectors and Gene Therapy

Free Download Lentiviral Vectors and Gene Therapy by David Escors , Karine Breckpot , Frederick Arce , Grazyna Kochan , Holly Stephenson
English | PDF (True) | 2012 | 110 Pages | ISBN : 3034804016 | 1.9 MB
Gene therapy was conceived during the early and mid part of the 20th century. At first, it was considered a revolutionary biomedical procedure, which could potentially cure any disease for which the molecular bases were understood. Since then, gene therapy has gone through many stages and has evolved from a nearly unrealistic perspective to a real life application. Clinical efficacy in humans was demonstrated at the beginning of this century after its successful application in small-scale clinical trials to cure severe immunodeficiency in children. However, their successes were overshadowed some time later by the occurrence of vector-related leukaemia in a number of treated children.